PHARMACEUTICAL INFORMATIONS

Selegiline

General Description : Increase your senior pet’s quality of life with this FDA-approved drug for canine senility and Cushing’s disease. Selegiline, a monoamine oxidase inhibitor (MAOI) provides help...

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General Description : Increase your senior pet’s quality of life with this FDA-approved drug for canine senility and Cushing’s disease. Selegiline, a monoamine oxidase inhibitor (MAOI) provides help for pets who may be showing certain kinds of aging. Five tablet strengths are available in blister packs of 30 tablets each.

What is this drug?

A monoamine oxidase inhibitor (MAOI)
Also known as L-Deprenyl
Given by mouth
Reasons for prescribing:

Used for the control of clinical signs of cognitive dysfunction syndrome (CDS), or senility in dogs and cats
Used for the control of clinical signs of Cushing’s disease caused by a pituitary tumor in dogs
What dogs/cats should not take this medication?

Not for use in dogs with behavior problems such as aggression
Not for use in dogs that have Cushing’s disease caused by some other reason than a pituitary tumor
Safety has not been established in breeding, pregnant or nursing pets
If your pet has had an allergic reaction to selegiline or like products
Directions:

Read and follow the label carefully. Ideally, give the medication at the same time(s) daily.

Do not give your pet aged cheese while on selegiline. It can cause severe high blood pressure or death.

Give the exact amount prescribed and only as often as directed. In dogs it is usually given once daily in the morning, and once in the evening for cats .

Give this medication for as long as veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.

Cushing’s disease: Your veterinarian will need to perform lab tests prior to initiating treatment with selegiline. After treatment, if you see no improvement in your dog within a month or two, contact your veterinarian for re-evaluation.

Baseline and periodic blood testing may be necessary to assess the pet’s health and response to selegiline.

Ensure your pet has fresh, clean drinking water at all times.

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is 16 hours or less before the next scheduled dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
What are the risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements (or unusual food) that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Keep this and all medication out of reach of children and pets. Not for human use.

Call your physician immediately if you accidentally take this product.

Potential side effects:

Decreased appetite, drooling, vomiting and diarrhea, fatigue, confusion, restlessness, hearing loss, trembling, itching, hair loss, anemia (pale gums)
Repetitive behaviors (ex. walking in circles, obsessive interest in something)
If these symptoms persist or you notice anything else unusual, contact your veterinarian
Contact your veterinarian immediately if your pet’s eyes respond slowly to changes in light (ie. pupils do not get smaller with bright light) or your pet pants excessively, or has an allergic reaction (difficulty breathing, hives, agitation, swelling of the lips, tongue or face)
Can this drug be given with other drugs?

Yes, but possible interactions may occur with ephedrine or other MAOI’s (ex. amitraz – tick collars)
Discontinue selegiline at least 14 days prior to initiating treatment with some narcotic pain killers (ex. Demerol), phenylpropanolamine, SSRI’s (ex. fluoxetine) and tricyclic antidepressants (ex. amitriptyline)
Some narcotic pain killers (ex. Demerol), phenypropanolamine, SSRI’s (ex. fluoxetine) and tricyclic antidepressants (ex. amitriptyline) should not be used within 5 weeks of administering selegiline
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Overdosing?

Contact your veterinarian immediately if pet receives more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, selegiline should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about selegiline. If you have any questions or concerns about selegiline or the condition it was prescribed for, contact your veterinarian.

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Spinosad

General Description : A fast acting, beef-flavored chewable tablet to give your dog month long flea protection. Spinosad starts to kill fleas within 30 minutes of application, and eliminates 100% of...

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General Description : A fast acting, beef-flavored chewable tablet to give your dog month long flea protection. Spinosad starts to kill fleas within 30 minutes of application, and eliminates 100% of your dog’s fleas within 4 hours. Safe for use in dogs older than 14 weeks. The active ingredient, spinosad, is environmentally friendly and FDA approved. Packages are available in five sizes, each containing a six month supply.

What is this drug?

A biologic product, an ultra-fast flea-killing tablet
Classified by the USDA as an organic substance (considered a drug, not an insecticide)
Given by mouth
Reasons for prescribing:

For the prevention and treatment of flea infestation on the dog
Prevents future infestations when used monthly
Does not kill other internal or external parasites
What dogs/cats should not take this medication?

This product is not approved for nor recommended for use in cats
Use with caution in dogs with pre-existing epilepsy
Dogs less than 14 weeks of age
Use with caution in breeding, pregnant or nursing dogs
The safe use of spinosad in male breeding dogs has not been established
If your pet has had an allergic reaction to spinosad or like products
Directions:

Give with food monthly for maximum effectiveness.

Treatment may begin at any time of the year. Ideally, begin administration one month before fleas become active, and then continue monthly throughout flea season. Should your area experience fleas year-round, give spinosad monthly without interruption.

To minimize re-infestation, treat all pets in the house with an approved product.

You can play with your dog immediately after treatment. There is no need to isolate your pet.

Read and follow the label carefully.

What if a dose is missed?

If a dose is missed, give it as soon as you can and resume a monthly dosing schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
What are the risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store at 20-25°C (68-77°F), excursions permitted between 15-30°C (59-86°F).

Keep this and all medication out of reach of children and pets. Not for human use.

Call your physician immediately if you accidentally take this product.

Potential side effects:

The most common adverse reaction is vomiting. If your dog vomits within 1 hour of administration, re-dose with another full dose
Other side effects include decreased or increased appetite, lethargy, diarrhea, cough, increased thirst, vocalization, redness of the skin, hyperactivity and drooling.
Synthetic beef flavor is actually derived from pork protein and hydrolyzed soy. Use with caution in dogs allergic to pork.
If these symptoms persist or you notice anything else unusual, contact your veterinarian
Can this drug be given with other drugs?

Yes, but possible interactions may occur with high doses of ivermectin
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Overdosing?

Contact your veterinarian immediately if pet eats more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, spinosad should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about spinosad. If you have any questions or concerns about spinosad or the condition it was prescribed for, contact your veterinarian.

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Sucralfate

General Description : Sucralfate is an oral anti-ulcer drug used in dogs and cats to coat ulcers in the gastrointestinal tract to protect them from stomach acid and allow them to heal. Sucralfate is...

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General Description : Sucralfate is an oral anti-ulcer drug used in dogs and cats to coat ulcers in the gastrointestinal tract to protect them from stomach acid and allow them to heal. Sucralfate is helpful in many conditions associated with stomach ulcers (ex. poison ingestion, kidney or liver failure, cancer and megaesophagus). Sucralfate is available as an oral liquid or as tablets.

What is this drug?

Sucralfate is an anti-ulcer drug; a sucrose aluminum hydroxide compound
Sucralfate is given by mouth
Reasons for prescribing:

Used to coat ulcers in the mouth, stomach, upper small intestine and esophagus. It protects the ulcer from stomach acid and helps in the healing process too.
May be used in any condition associated with stomach ulcers (ex. poison ingestion, kidney and liver failure, some cancers and megaesophagus)
Often prescribed with ulcer-causing medications (ex. aspirin, piroxicam)
What dogs/cats should not take this medication?

Contistipated animals or those known to have slow movement of food through the digestive system (ex. those with megacolon)
Use cautiously in pregnant and nursing animals
Pets known to have had an allergic reaction to sucralfate
Directions:

This medication should be given on an empty stomach (at least 1 hour before a meal, or two hours after).

Shake liquid medication well. Tablets are usually crushed to allow better absorption.

Give medication as directed by your veterinarian. This medication is usually givenfour times daily. This ensures continuous protection for the ulcer(s). One dose protects for 6 hours only.

Read and follow the label carefully.

Give the exact amount prescribed and only as often as directed. Missed doses reduce the effectiveness of therapy.

The length of therapy depends greatly upon the disease condition as well as the pet’s response to sucralfate.

Call ahead for refills.

Ideally, give the medication at the same time daily.

What if dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
Risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store sucralfate in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Shake liquids well before using.

Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.

Potential side effects:

Constipation
With long term use, one of the ingredients (aluminum) may build up and cause the bones to weaken or have an effect on the brain
It is important to stop therapy and contact your veterinarian immediately if you think you pet has a medical problem or side effect from this product’s therapy
Can this drug be given with other drugs?

Yes, but possible interactions may occur with cimetidine, digoxin, fluorquinolone antibiotics (enrofloxacin,, marbofloxacin,orbifloxacin), phenytoin and tetracycline.
The above drugs can still be used, but give the sucralfate dose 2 hours before or after the other drug(s).
Since sucralfate requires an acid environment to work, give sucralfate 30 minutes before cimetidine or an antacid.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian

Overdosing?

Contact your veterinarian immediately if pet eats more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens (blood in the vomit or stools) despite this treatment.

As with all prescribed medicines, sucralfate should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about sucralfate. If you have any questions or concerns about sucralfate or for the condition it was prescribed, contact your veterinarian.

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Tepoxalin

General Description: Tepoxalin is an oral nonsteroidal anti-inflammatory drug (NSAID) used in dogs to control pain and inflammation due to osteoarthritis. While tepoxalin is not a cure for...

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General Description: Tepoxalin is an oral nonsteroidal anti-inflammatory drug (NSAID) used in dogs to control pain and inflammation due to osteoarthritis. While tepoxalin is not a cure for osteoarthritis, it can control the pain and inflammation of osteoarthritis and improve your dog’s mobility. This medication should be given with food or shortly after feeding. Response varies but in most dogs, improvement will be seen in a few days. Tepoxalin is available in 50 mg, 100 mg and 200 mg tablets.

What is this drug?

• Tepoxalin is a nonsteroidal anti-inflammatory drug (NSAID)

• Available as a rapidly disintegrating tablet and is given to dogs by mouth.

Reasons for prescribing?

• Used to reduce pain and inflammation (soreness) due to osteoarthritis in dogs [signs include limping or lameness, decreased activity or exercise (reluctance to stand, climb stairs, jump or run, or difficulty in performing these activities), stiffness or decreased movement of joints]

What dogs/cats should not take this medication?

• Tepoxalin should be given to dogs only

• Has had an allergic reaction to the active ingredient tepoxalin

• Has had an allergic reaction to aspirin or other NSAIDs (for example, carprofen, etodolac or phenylbutazone) such as hives, facial swelling, or red or itchy skin

Directions:

Tepoxalin should be given according to your veterinarian’s instructions. Your veterinarian will tell you what amount of tepoxalin is right for your dog and for how long it should be given.

Tepoxalin should be given by mouth. Tepoxalin should be administered with food or shortly (within 1 to 2 hours) after your dog has eaten.

While tepoxalin is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog’s mobility.

In most dogs, improvement can be seen in a matter of days.

If tepoxalin is discontinued or not given as directed, your dog’s pain and inflammation may return.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

• The signs of OA you have observed (for example, limping, stiffness)

• The importance of weight control and exercise in the management of OA

• What tests might be done before tepoxalin is prescribed

• How often your dog may need to be examined by your veterinarian

• The risks and benefits of using tepoxalin

Tell your veterinarian about:

• Experienced side effects from tepoxalin or other NSAIDs, such as aspirin

• Digestive upset (vomiting and/or diarrhea)

• Liver and kidney disease

• A bleeding disorder (for example, Von Willebrand’s disease)

• Any other medical problems or allergies that your dog has now or has had

• All medicines that you are giving your dog or plan to give your dog, including those you can get without a prescription

• If your dog is pregnant, nursing or if you plan to breed your dog

Storage and Warnings:

Store in a tight, light resistant, childproof container at room temperature away from heat and direct sunlight.

For use in dogs only. People should not take tepoxalin. Keep tepoxalin and all medicine out of reach of children.

Call your physician immediately if you accidentally take tepoxalin.

Possible side effects?

Tepoxalin Tablets, like other drugs, may cause some side effects. Serious side effects have been reported in dogs taking NSAIDs, including Tepoxalin Tablets. Serious side effects associated with NSAID therapy can occur with or without warning and in rare situations result in death.

The most common side effects associated with Tepoxalin Tablet therapy involve the digestive tract (for example, vomiting, diarrhea, or bleeding). Liver or kidney problems have also been reported with certain NSAIDs. Look for the following side effects that can indicate your dog may be having a problem with NSAID therapy or may have another medical problem:

• Decrease or increase in appetite

• Vomiting

• Change in bowel movements (such as diarrhea, or black, tarry, or bloody stools)

• Change in behavior (such as decreased or increased activity level, incoordination, seizure, or aggression)

• Yellowing of gums, skin, or whites of the eyes (jaundice)

• Change in drinking habits (frequency or amount consumed)

• Change in urination habits (frequency, color, or smell)

• Change in skin (redness, scabs, or scratching)

It is important to stop therapy and contact your veterinarian immediately if you think your dog has a medical problem or side effect from tepoxalin therapy. If you have additional questions about possible side effects, talk to your veterinarian or call 1-800-224-5318.

Can this drug be given with other drugs?

Tepoxalin should not be given with other NSAIDs (for example, aspirin, carprofen, phenylbutazone or etodolac) or steroids (for example, cortisone, prednisone, dexamethasone, or triamcinolone).

Overdosing?

Contact your veterinarian immediately if your dog eats more than the prescribed amount of tepoxalin.

What else should I know?

This sheet provides a summary of information about tepoxalin. If you have any questions or concerns about tepoxalin or osteoarthritis pain, talk to your veterinarian.

As with all prescribed medicines, tepoxalin should only be given to the dog for which it was prescribed. It should be given to your dog only for the condition for which it was prescribed. It is important to periodically discuss your dog’s response to tepoxalin at regular check ups.

Your veterinarian will best determine if your dog is responding as expected and if your dog should continue receiving tepoxalin.

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Tramadol

General Description : Tramadol is used to relieve moderate to moderately severe pain associated with surgery, or chronic pain in joints or due to cancer. Tramadol is available in 50 mg tablets.

What...

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General Description : Tramadol is used to relieve moderate to moderately severe pain associated with surgery, or chronic pain in joints or due to cancer. Tramadol is available in 50 mg tablets.

What is this drug?

An analgesic or pain reliever
Given by mouth
Controlled drug in AR, KY, ND, OH and WY
Reasons for prescribing:

To treat acute or chronic pain (ex. post surgery, joint or cancer)
May be prescribed as an alternative to NSAIDs or in addition to an NSAID
What dogs/cats should not take this medication?

Safety in pregnant or nursing animals is unknown
Do not use in patients with head trauma or with a history of seizures
Use with caution in pets with respiratory depression, liver or kidney disease
If your pet has had an allergic reaction to tramadol, codeine or other narcotics
Directions:

Do not use Ultracet® brand on cats.

Read and follow the label carefully.

Give the exact amount prescribed and only as often as directed. It is usually giventwo or four times a day .

Ideally, give the medication at the same time(s) daily.

Tramadol may be given with or without food, but do not crush tablets.

If your pet is on this medication long-term (several weeks), do not abruptly stop giving the medication without consulting your veterinarian. Your pet will experience unpleasant withdrawal symptoms if the dose is not tapered down slowly.

Ensure your pet has plenty of fresh drinking water.

Call ahead for refills.

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
What are the risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Keep this and all medication out of reach of children and pets.

Call your physician immediately if you accidentally take this product

Potential side effects:

Do not use Ultracet® brand on cats.
Occasional sedation and respiratory depression
Loss of appetite, nausea, vomiting and constipation
Cats: dilated pupils and/or disorientation
If you see any of these symptoms or any behavior changes or notice anything else unusual, contact your veterinarian
Can this drug be given with other drugs?

Yes, but possible interactions may occur with amitraz (ex. Mitaban®, Preventic® tick collar), cold or allergy medication, digoxin, ketoconazole, monamine oxidase inhibitors [(MAOIs), ex. Anipryl®], muscle relaxers, narcotic pain medications, oral dietary supplements, selective serotonin reuptake inhibitors [(SSRIs) ex. Reconcile®], tricyclic medications (ex. Clomicalm®) and warfarin.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Overdosing?

Contact your veterinarian immediately if pet receives more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, tramadol should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about tramadol. If you have any questions or concerns about tramadol or the condition it was prescribed for, contact your veterinarian.

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Silymarin

General Description : Silymarin is used in pets to treat a variety of liver diseases. It has also been found to have liver protectant properties in cases where toxic agents have been consumed....

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General Description : Silymarin is used in pets to treat a variety of liver diseases. It has also been found to have liver protectant properties in cases where toxic agents have been consumed. Numerous herbal brands are available as seed extracts. Veterinary brands may include Vitamin E and phosphatidyl choline or SAMe. Consult with your veterinarian to choose the best product for your pet.

What is this drug?

Acts as an antioxidant and free radical scavenger
Protects and supports healthy liver function
Given by mouth
Reasons for prescribing:

Used in the treatment of various liver diseases. It may not be helpful in all liver diseases but it is a safe substance if used with your veterinarian’s advice
Has been shown to be useful in the some poisonings that affect the liver
What dogs/cats should not take this medication?

Use with caution in pregnant and nursing animals as safety is unknown
If your pet has had an earlier allergic reaction to silymarin or is allergic to similar plants (ex. ragweed, marigold, daisies, etc.)
Directions:

Read and follow the label carefully.

Silymarin is usually given once daily and can be used long-term.

Check on the product label if the product should be given with or without food.

Nutraceutical products are not regulated by the FDA. As such, they have not been required to go through the same rigorous testing for efficacy that drugs undergo. There may be great variation in strength between brands or even between batches of the same brand. Yet there are many quality products on the market that are made by reputable companies. Consult with your veterinarian to choose a sound product for your pet.

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
What are the risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Keep this and all medication out of reach of children and pets.

Potential side effects:

This medication is usually well tolerated
Stomach upset is possible (nausea, loss of appetite, vomiting or diarrhea) especially at high doses
Humans report stomach upset, headaches, joint pain and weakness
If you notice anything unusual, contact your veterinarian
Can this drug be given with other drugs?

Yes, there are no known drug interactions with silymarin
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Overdosing?

Contact your veterinarian immediately if pet receives more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, silymarin should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about silymarin. If you have any questions or concerns about silymarin or the condition it was prescribed for, contact your veterinarian.

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Spironolactone

General Description: Spironolactone is a diuretic used in dogs and cats to remove excess fluid from the body. This drug has been chosen because your pet has not responded to other types of diuretics. ...

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General Description: Spironolactone is a diuretic used in dogs and cats to remove excess fluid from the body. This drug has been chosen because your pet has not responded to other types of diuretics. Unlike other diuretics, spironolactone does not cause blood potassium to be lost.

What is this drug?

Spironolactone is a diuretic (helps the body lose water via increased urine production)
Spironolactone is given by mouth
Reasons for prescribing:

Because this drug helps remove excessive fluids from the body, it is useful in the treatment of congestive heart failure, ascites and edema
What dogs/cats should not take this medication?

Pets with high blood potassium levels, or those with, or at risk for, Addison’s disease (hypoadrenocorticism) or diabetes
Use with caution in pets with kidney or liver disease
Pets taking the drug mitotane (treatment for Cushing’s disease)
Pregnant and nursing pets
Pets known to have had an allergic reaction to spironolactone
Directions:

Give this medication with food to increase its absorption and lessen stomach upset. Ideally, give the medication at the same time daily.

Give medication as directed by your veterinarian. This medication is usually givenonce or twice daily. Give the exact amount prescribed and only as often as directed. Missed doses reduce the effectiveness of therapy. Do not suddenly stop this medication.

This product may be provided to you as tablets. If it is difficult for you to administer tablets to your pet, your veterinarian may be able to have it formulated as an oral liquid or a transdermal gel.

Ensure your pet has plenty of food and fresh, clean drinking water while taking spironolactone. It is important that your pet eats and drinks well to decrease the likelihood of side effects. Speak to your veterinarian if your pet does not eat or drink well.

Your pet will have to urinate more frequently than normal and ‘accidents’ are possible.

What if dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
Risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Store oral liquids in the refrigerator for no more than 30 days. Shake well before use.

Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.

Potential side effects:

Dehydration with excessive thirst and decreased urine production
Electrolyte (salts) imbalances may occur. Weakness or lethargy could indicate potassium levels have become too high. Weakness and confusion could indicate low sodium levels. Vomiting and diarrhea occurs in some animals. Contact your veterinarian if your pet shows these effects.
If you notice anything unusual, contact your veterinarian
Can this drug be given with other drugs?

Yes, but possible interactions may occur with ACE inhibitors (enalapril, captopril or lisonopril), ammonium chloride, aspirin, digoxin, epinephrine, indomethacin, glipizide, mitotane, NSAIDs, other diuretics or heart or blood pressure medications, potassium supplements, protein-binding drugs
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Overdosing?

Contact your veterinarian immediately if pet consumes more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, spironolactone should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed. It is important to periodically discuss your pet’s response to spironolactone at regular check ups. Your veterinarian will best determine if your pet is responding as expected and if your pet should continue receiving spironolactone.

This is just a summary of information about spironolactone. If you have any questions or concerns about spironolactone or for the condition it was prescribed, contact your veterinarian.

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Sulfasalazine

General Description: Sulfasalazine is a combination of a sulfa antibiotic and a salt of salicylic acid (aspirin). It is used in dogs and cats to treat colitis or bowel inflammation. Give this...

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General Description: Sulfasalazine is a combination of a sulfa antibiotic and a salt of salicylic acid (aspirin). It is used in dogs and cats to treat colitis or bowel inflammation. Give this medication with food. Sulfasalazine is available as an oral suspension or as tablets.

What is this drug?

An anti-inflammatory; a combination of a sulfa antibiotic and a salt of salicylic acid (aspirin)
Given by mouth
Reasons for prescribing:

Colitis or bowel inflammation (bloody or mucous diarrhea with urgency and occasionally, vomiting)
What dogs/cats should not take this medication?

Cats are sensitive to salicylates. Dose adjustments will be made to compensate.
Pets known to have had an allergic reaction to the sulfasalazine, salicylates (aspirin), or other sulfa drugs
Dehydrated animals (as kidney stone formation may occur)
Anemic patients, or those who have been anemic in the past
Pets with liver or kidney disease
Use with caution in breeds pre-disposed to ‘dry-eye’
Use with caution in breeding male dogs; may affect fertility
Pregnant or nursing animals
Directions:

For liquids, shake well before accurately measuring the dose.

Give this medication with food.

Give medication as directed by your veterinarian. Dogs usually receive sulfasalazine two or three times daily . Cats usually receive it once a day.

The dose may be gradually increased until the diarrhea resolves, and then decreased gradually when bowel movements are normal.

Give the exact amount prescribed and only as often as directed. Missed doses reduce the effectiveness of therapy.

Sulfasalazine is a brightly-colored medication. If your pet vomits, the orange dye is not easily removed from carpeting/fabrics.

Ensure your pet has fresh, clean drinking water at all times.

Ideally, give the medication at the same time daily.

What if dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
Risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store sulfasalazine in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.

Pet owners allergic to sulfa drugs and/or aspirin-like should avoid handling this drug.

Potential side effects:

Allergic reaction (difficulty breathing, closing of throat, hives, swollen lips, tongue or face; or fever, abdominal pain, cramping, bloody diarrhea; or sore throat, fever or yellow eyes). Stop the medication and seek veterinary medical attention immediately.
The only likely side effect is decreased tear production. Watch for eye discomfort (squinting, redness, blinking, eye rubbing, increased discharge). This usually only occurs with long-term therapy.
Other side-effects noted with sulfa drug administration are:

Decreased appetite and vomiting (cats)
Joint inflammation (arthritis, fever, muscle soreness)
Skin rashes and itchiness
Liver failure (nausea; yellowing of gums, skin, eyes)
Kidney failure (increase thirst and urination)
Blood abnormalities (bleeding tendencies, pale gums, fatigue, or fever of 103-105° F)
It is important to stop therapy and contact your veterinarian immediately if you think you pet has a medical problem or side effect from this product’s therapy.

Can this drug be given with other drugs?

Yes, but possible interactions may occur with antacids, aspirin, digoxin, folic acid methotrexate (a cancer chemotherapeutic), phenylbutazone, phenytoin, probenecid, thiazide diuretics and warfarin (an anticoagulant).
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Overdosing?

Contact your veterinarian immediately if pet eats more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, sulfasalazine should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about sulfasalazine. If you have any questions or concerns about sulfasalazine or for the condition it was prescribed, contact your veterinarian.

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Theophylline

General Description : Theophylline is used as a bronchodilator in dogs and cats with asthma or other respiratory conditions. It opens the lung’s air passages by relaxing the muscles in the lungs and...

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General Description : Theophylline is used as a bronchodilator in dogs and cats with asthma or other respiratory conditions. It opens the lung’s air passages by relaxing the muscles in the lungs and chest. It may also be used with other medications in the treatment of cardiac disease. Theophylline is sold by prescription as an extended release tablet.

What is this drug?

A bronchodilator; a member of the methylxanthine group of biochemicals
Given by mouth
Reasons for prescribing:

To treat heart failure, asthma, bronchitis and pulmonary edema in dogs and cats. It opens air passages in the lungs, increases the contraction strength of the diaphragm and clears mucus from the respiratory tract.
What dogs/cats should not take this medication?

Pregnant or nursing pets
Use with caution in patients with severe heart disease, cardiac arrhythmias, GI ulcers, hyperthyroid, glaucoma, high blood pressure, a history of seizures, liver or kidney disease
Use with caution in the very young, obese, debilitated or very old
If your pet has had an allergic reaction to theophylline, ethylenediamine or xanthines including theobromine and caffeine
Directions:

Read and follow the label carefully.

Give on an empty stomach , 1 hour before or two hours after a meal.

Extended release tablets should be swallowed whole and not crushed or chewedto ensure that the medication is released slowly.

Give the exact amount prescribed and only as often as directed. It can be dangerous in high doses.

In dogs, this medication is usually given twice a day. In cats, it is given once a day(usually at bedtime in asthmatic cats).

Give this medication for as long as veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian.

It is not uncommon for pets to initially experience nervousness or an upset stomach from this drug. These side effects will disappear in a short time. If they return, tell your veterinarian.

Call ahead for refills.

Ideally, give the medication at the same time(s) daily.

Ensure your pet has plenty of fresh, clean drinking water.

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
What are the risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Refrigerate oral suspensions and gummie chews. Store all other forms in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight. Protect from freezing.

Keep this and all medication out of reach of children and pets.

Call your physician immediately if you accidentally take this product.

Potential side effects:

Restlessness or caffeine-type jitters. A lower starting dose may minimize this effect
Mild stomach upset, racing heart with abnormal heart rhythm (not all patients)
Diuretic effect in some patients (increased thirst and urination)
Seizures and heart rhythm problems can occur with severe intoxication
There seems to be variations between brands. Some brands last too long, some not long enough. When the prescription is refilled, ensure that you are getting the correct brand and type as prescribed by your veterinarian.
If your pet shows any of these symptoms or you notice anything else unusual, contact your veterinarian
Can this drug be given with other drugs?

Yes, but possible interactions may occur with allopurinol, antacids, beta-blockers, cimetidine, ciprofloxacin, clindamycin, erythromycin, enrofloxacin, ephedrine, erythromycin, halothane, ketamine, lincomycin, lithium carbonate, pancuronium, phenobarbital, phenytoin and thiabendazole
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Overdosing?

Contact your veterinarian immediately if pet receives more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, theophylline should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about theophylline. If you have any questions or concerns about theophylline or the condition it was prescribed for, contact your veterinarian.

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Trilostane

General Description : A short-acting adrenocortical suppressant for oral use in dogs. Trilostane blocks the adrenal gland from making too many steroids. Although steroids are important for various...

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General Description : A short-acting adrenocortical suppressant for oral use in dogs. Trilostane blocks the adrenal gland from making too many steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

What is this drug?

An adrenocortical suppressant
Given by mouth
Reasons for prescribing:

For the treatment of both pituitary-dependent or adrenal-dependent hyperadrenocorticism (Cushing’s disease) in dogs
Trilostane is a treatment but not a cure for this condition
What dogs/cats should not take this medication?

This product is for dogs only
Use with caution in pets with anemia, liver or kidney disease
Do not use in pregnant dogs
Safe use has not been established in nursing dogs or breeding males
If your pet has had an allergic reaction to trilostane or like products before
Directions:

Read and follow the label carefully.

Give the exact amount prescribed and only as often as directed. Give trilostaneonce daily with the morning meal. This will make it easier to perform future blood testing.

Do not open or divide capsules.

Baseline blood work to assess your pet’s health before starting this drug is recommended. Periodic blood work to monitor its effect is also advised if long-term therapy is necessary. Dose adjustments will be made based upon the blood results and an assessment of how your dog is responding clinically.

Expect to see the signs of hyperadrenocorticism (lethargy, increased drinking, eating, or urination) improve within the first 2 weeks of treatment. Skin and hair loss changes may take several months to improve.

Most dogs remain on trilostane for the remainder of their life.

Call ahead for refills.

What if a dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
What are the risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced anemia, liver or kidney disease now or ever
If your pet has experienced diabetes or any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store in a childproof container at room temperature away from heat and direct sunlight.

Keep this and all medication out of reach of children and pets. This medication is potentially harmful to humans. Do not handle this product if you are pregnant or trying to conceive. Wash your hands well after handling.

Call your physician immediately if you accidentally take this product.

Potential side effects:

This medication is usually well tolerated by dogs
Most common effects: lethargy, weakness, loss of appetite in first few days, vomiting and diarrhea
More serious effects: severe depression, hemorrhagic diarrhea, collapse, hypoadrenocortical crises or adrenal necrosis/rupture, death
Rare cases of acute death or hypoadrenocorticism
If you notice anything unusual, stop therapy and contact your veterinarian
Can this drug be given with other drugs?

Yes, but possible interactions may occur with ACE inhibitors and potassium-sparing diuretics (ex. spironolactone).
An interval of at least one month should be observed after stopping the administration of mitotane and starting trilostane. Close monitoring of adrenal function is advised.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.
Overdosing?

Contact your veterinarian immediately if pet eats more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, trilostane should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about trilostane. If you have any questions or concerns about trilostane or the condition it was prescribed for, contact your veterinarian.

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Trimethoprim with Sulfamethoxazole or Sulfadiazine

General Description: Trimethoprim sulfa is a n oral broad-spectrum antibiotic used in dogs and cats to treat many infections, including protozoal and skin infections. This medication can be given...

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General Description: Trimethoprim sulfa is a n oral broad-spectrum antibiotic used in dogs and cats to treat many infections, including protozoal and skin infections. This medication can be given with or without food. Trimethoprim sulfa is available as an o ral paste or suspension, a powder or as tablets.

What is this drug?

Trimethoprim sulfa is a broad-spectrum antibiotic
Trimethoprim sulfa is given by mouth
Reasons for prescribing:

Used to treat many infections, including protozoal and skin infections
Is less likely to cause diarrhea than some antibiotics
What dogs/cats should not take this medication?

Pets with a history of liver disease, anemia or other blood abnormalities
Pets with a history of kidney disease or kidney stones
Dehydrated pets
Pregnant or nursing animals
Pets known to have had an allergic reaction to trimethoprim sulfa or other sulfonamides
Directions:

Ensure you pet has fresh, clean drinking water at all times.

For liquids, shake well before accurately measuring the dose.

Give this medication with of without food.

Give medication as directed by your veterinarian. This medication is usually given once or twice daily.

Cats don’t like the taste of trimethoprim sulfa and will drool profusely. Providing the drug as a capsule or some other dosage form may facilitate easier administration. After administration, watch the pet closely to ensure the entire dose was consumed

Give the exact amount prescribed and only as often as directed. Missed doses reduce the effectiveness of therapy.

Give this medication for as long as your veterinarian directs. Finish the entire course of treatment.

Ideally, give the medication at the same time daily.

What if dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
Risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store trimethoprim sulfa in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

Store liquids in the refrigerator. Discard any unused liquid after 14 days. Shake liquids well before using.

Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.

Pet owners allergic to trimethoprim sulfa and/or other antibiotics should avoid handling this drug.

Potential side effects:

Side effects are rare, but if they occur they can be serious. The following reactions occur not because of the amount of drug given, but the individual pet’s sensitivity to trimethoprim sulfa:

Vomiting, diarrhea, loss of appetite, facial swelling
Joint inflammation (arthritis, fever, muscle soreness), especially in Dobermans
Skin rashes and itchiness
Liver failure (nausea; yellowing of gums, skin, eyes)
Inability to produce adequate tears or ‘dry eye’ (increased blinking or discharge, eye rubbing)
Sulfa bladder or kidney stones
Blood abnormalities (bleeding tendencies, pale gums, fatigue, or fever of 103-105° F)
Dogs can develop hypothyroidism with long-term use
It is important to stop therapy and contact your veterinarian immediately if you think you pet has a medical problem or side effect from this product’s therapy
Can this drug be given with other drugs?

Yes, but possible interactions may occur with antacids, aspirin, blood thinners, glipizide, methotrexate, phenylbutazone, probenecid and thiazide diuretics.
Trimethoprim sulfa should not be used in conjunction with cyclosporine.
Trimethoprim sulfa may interfere with thyroid function testing. If your pet needs to have his thyroid levels checked, you may need to discontinue this medication prior to the test.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Overdosing?

Contact your veterinarian immediately if pet eats more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, trimethoprim sulfa should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about trimethoprim sulfa. If you have any questions or concerns about trimethoprim sulfa or for the condition it was prescribed, contact your veterinarian.

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Tylosin

General Description: Tylosin is a n oral macrolide antibiotic used in dogs and cats to treat many infections (ex. ear, respiratory, skin and genitourinary tract infections). Tylosin may also be used...

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General Description: Tylosin is a n oral macrolide antibiotic used in dogs and cats to treat many infections (ex. ear, respiratory, skin and genitourinary tract infections). Tylosin may also be used to treat some types of diarrhea. Tylosin is available as a powder which can be mixed with your pet’s food, or it can be compounded by a special pharmacy into capsules which may be more readily accepted by your pet.

What is this drug?

Tylosin is a macrolide antibiotic
Tylosin is given by mouth
Reasons for prescribing:

Useful to treat a variety of bacterial infections, including ear, respiratory, skin, urinary and uterine infections plus certain types of diarrhea in dogs and cats
For the treatment of chronic diarrhea
What dogs/cats should not take this medication?

Pets known to have had an allergic reaction to tylosin or other antibiotics
Use with caution in pregnant and lactating animals
Directions:

This medication is usually given with food two times daily.

Tylosin is only available commercially as a powder. Unfortunately, due to its natural bitter taste, hiding it in the pet’s food may not be effective. Your veterinarian may instruct you on how to administer the powder mixed in food or water, or perhaps have it compounded into capsules that will be more readily accepted by your pet.

Give the exact amount prescribed and only as often as directed. Missed doses reduce the effectiveness of therapy.

Give this medication for as long as your veterinarian directs. Finish the entire course of treatment.

Ideally, give the medication at the same time daily.

What if dose is missed?

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

When will your pet need to be rechecked
What tests may need to be performed prior to and during treatment with this drug
Risks and benefits of using this drug
Tell your veterinarian about:

If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
If your pet is pregnant or nursing or if you plan to breed your pet
Storage and Warnings:

Store powder and capsules in a tight, light resistant, childproof container in a dry place at room temperature away from heat and direct sunlight.

Discard liquid solutions made with tylosin after three days.

Not for use in horses.

People should not take this product. Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.

Pet owners allergic to macrolides and/or other antibiotics should avoid handling this drug.

Potential side effects:

Decrease in appetite, nausea, vomiting and slight worsening of existing diarrhea
It is important to stop therapy and contact your veterinarian immediately if you think your pet has a medical problem or side effect from this product’s therapy
Can this drug be given with other drugs?

Yes, but possible interactions may occur with digoxin.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Overdosing?

Contact your veterinarian immediately if pet eats more than the prescribed amount.

What else should I know?

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, tylosin should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about tylosin. If you have any questions or concerns about tylosin or for the condition it was prescribed, contact your veterinarian.

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Texas West Animal Health

16367 South FM 4,

Santo, TX 76472

Phone. 940-769-2222

Fax. 866-632-3365

Email. texaswestvet@gmail.com