General Description: Ivermectin + pyrantel pamoate + praziquantel is a combination of 3 anti-parasitic drugs used monthly in dogs to prevent heartworm infection and for the treatment and control of tapeworms, roundworms and hookworms. This product may be given with or without food. Chewable tablets are available in different strengths.
What is this drug?
Ivermectin, pyrantel pamoate and praziquantel is a combination of three anti-parasite drugs
Ivermectin, pyrantel pamoate and praziquantel is given by mouth
Reasons for prescribing:
For heartworm prevention in dogs
For treatment and control of roundworms, hookworms and tapeworms
What dogs/cats should not take this medication?
For use in dogs only
Puppies less than 8 weeks of age
Use with caution in sick, debilitated or underweight animals and dogs weighing less than 10 pounds
This product has not been evaluated in pregnant or nursing bitches
Safe for use in Collies, Australian shepherds, Old English sheepdogs, Shelties and any of these crossbreed dogs if given the regular monthly heartworm preventative dosing level
Pets known to have had an allergic reaction to ivermectin, pyrantel pamoate or praziquantel or like products
Give this medication with or without food. Ensure that your pet consumes the entire dose.
Give medication as directed by your veterinarian. This medication is often given seasonally.
As a heartworm preventative, this medication is given once a month, beginning within a month after the pet’s first exposure to mosquitoes. The medication kills the parasites acquired during the previous month. The final dose should be given within a month of the last exposure to mosquitoes.
Monthly treatment also provides effective treatment and control of roundworms, hookworms and whipworms.
Ideally, give the medication on or about the same day each month.
What if dose is missed?
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time. If you miss more than 8 weeks in a row, give the drug as soon as you remember, but you should have your pet’s blood tested for heartworms within 6 months (as infection may have occurred).
What to tell/ask veterinarian before giving medication?
Talk to your veterinarian about:
When will your pet need to be rechecked
Whether a blood test will need to be performed prior to treatment with this drug
Risks and benefits of using this drug
Tell your veterinarian about:
If your pet has experienced side-effects on other drugs/products
If your pet has experienced digestive upset now or ever
If your pet has experienced liver or kidney disease now or ever
If your pet has experienced any other medical problems or allergies now or ever
All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medicines can be given together.
Storage and Warnings:
Store in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
People should not take this product. Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product.
Potential side effects:
When the parasites begin to die off, the animal may experience a mild hypersensitivity reaction including diarrhea
Self-limiting reactions may include lethargy, limpness, salivation, shaking, vomiting, diarrhea, decreased appetite, staggering, licking lips and belching 20 minutes to 72 hours following treatment
It is important to stop therapy and contact your veterinarian immediately if you think your pet has a medical problem or side effect from this product’s therapy
Can this drug be given with other drugs?
Yes, when this product is used at the recommended dose, there are no contraindicated drugs. When higher doses are used, interactions may occur with amitraz dips and collars (Mitaban®, Preventic®), spinosad (Comfortis™) or valiumor-related tranquilizers.
If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian
Contact your veterinarian immediately if pet consumes more than the prescribed amount.
What else should I know?
Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.
As with all prescribed medicines, this product should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed.
This is just a summary of information about ivermectin, pyrantel pamoate and praziquantel. If you have any questions or concerns about this product or for the condition it was prescribed, contact your veterinarian.